Add the entire 1 to 1 dilution of Safe-Guard AquaSol in water to the water in the stock suspension tank of the dosing pump. Each mL of Safe-Guard AquaSol contains 200 mg of fenbendazole. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). The required daily volume of product is calculated from the total estimated body weight [kg] of the entire group of chickens to be treated. Deworm as soon as you see the first symptoms of worm infestation among your chickens. Innovative manufacturing process enables easy, effective deworming for broilers, breeders, pullets and laying hens through oral administration via drinking water. For Patent Information: http://www.merck.com/product/patent/home.html. Ermagahd - not math! [Note: If the total volume of the 1 to 1 dilution needed exceeds the volume of the largest available measuring device, divide the total volume into two or more smaller batches of 1 to 1dilution, prepared following the steps below. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Three dose confirmation studies were conducted in European Union (EU), using 105Rhode Island Red breed hens (2 years old) for each study. At the end of the treatment phase, gross necropsies were performed on 12 hens from each group, and organs weights were evaluated. You can use Safeguard with baby chicks. Six pens of 2 pigs each were used per treatment group. (Oesophagostomum dentatum, O. quadrispinulatum); Total estimated body weight [kg] of the chickens to be treated 0.005 mL = mL Safe-Guard, Total estimated body weight [kg] of the pigs to be treated 0.011 mL = mL Safe-Guard. Look for telltale symptoms such as reduced feed intake, diarrhea, weight loss or gain, depression, and even decreased egg production among hens. See attached Product Information Insert for complete directions and warnings before using. Chickens should be regularly dewormed as early as 3 months old and as often as 2 or more times in a year. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS, or http://www.fda.gov/AnimalVeterinary/SafetyHealth. Fenbendazole is available as a medicated feed labelled for use in turkeys (Safe-Guard) or in a water-soluble formulation to be added to drinking water (Safe-Guard AquaSol) labelled for use in chickens. At the end of the treatment phase, gross necropsies were performed on 48 chickens from each group, and organs weights were evaluated. Zyfend A, 30 mL. After complete consumption of the medicated water, the animals should have access to non-medicated drinking water ad libitum. A common protocol was implemented in two different geographical locations and with two different investigators. A decrease of effectiveness over time may indicate the development of resistance to the dewormer administered. Swine: Swine intended for human consumption must not be slaughtered within 2 days from the last treatment. The efficacy against adult A. galli and H.gallinarum was 100% and 88.9%, respectively. Can Corid & Safeguard AQUASOL both be mixed in water at same time? The aquasol is formulated to be mixed in water, so it will stay suspended correctly. Add the entire 1 to 1 dilution of Safe-Guard AquaSol in water to the water in the stock suspension tank of the dosing pump. The margin of safety in laying hens was conducted in 144 laying hens. The volume of water in the stock suspension container has to be calculated taking as a basis the present injection rate of the dosing pump and the volume of drinking water usually consumed by the animals over a period of 3 to 24 hours. Do not freeze. Accidental exposure may result in skin and eye irritation. Family owned since 1975. It is specifically indicated by the manufacturer that Safe-Guard Aquasol should not be used for laying hens and replacement chickens that are groomed to become laying hens. Swine: Safe-Guard AquaSol must be administered orally to swine via the drinking water at a daily dose of 2.2 mg/kg BW (1 mg/lb) for 3 consecutive days. It is the active ingredient used in Safe-Guard Aquasol, and it works to combat adult-stage roundworms and adult-stage cecal worms in chickens. It is used for the treatment and control of adult roundworms in both broiler and replacement chickens that are grown to become breeding chickens and for the treatment and control of adult roundworms and cecal worms in breeding chickens. Following the use of any dewormer, effectiveness of treatment should be monitored. The control group received non-medicated drinking water. At concentrations from 5 mL up to 75 mL of product /L stock suspension (1,000 mg to 15,000mg fenbendazole/L) and within up to 8 hours during the treatment administration period no stirring of the stock suspension is required. A field effectiveness study was conducted in the EU in a flock of 13,244 Hy-Line layer breed replacement chickens (13 weeks old). In the study, the efficacy against adult A. galli and H. gallinarum was 98.7% and 99.2%, respectively. Histopathologic examinations were performed on 12 hens each from the control and 5 mg fenbendazole/kg body weight groups. No withdrawal time is required for consumption of eggs or meat from treated birds when administered according to label directions. USER SAFETY WARNINGS: Not for use in humans. The efficacy against adult A. galli and H.gallinarum was 100% and 88.9%, respectively. These two pigs had exhibited abnormal fecal consistency prior to treatment with FBZ. Histopathologic examinations were performed on 48 chickens each from the control and 5 mg fenbendazole/kg body weight groups. A third field effectiveness study was conducted in the US using 550 White Leghorn breed replacement chickens (14 weeks old). Every effort has been made to ensure the accuracy of the Safe-Guard AquaSol for Chickens information published above. Chickens: Safe-Guard AquaSol must be administered orally to chickens via the drinking water at a daily dose of 1 mg/kg BW (0.454 mg/lb) for 5 consecutive days. They're both fenbendazole, so couldn't I use the same dosage of safe-guard as aquasol, and skip egg withdrawal? The parasite management plan should be adjusted accordingly based on regular monitoring. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. Weaned, growing-finishing pigs of approximately 6 weeks of age were used in the study. My name is Patricia M. Harpole as a single mom I wanted to feel more financially stable and I knew that I can achieve that through farming. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The daily dose of 1 mg fenbendazole per kg BW (0.454 mg/lb) is equivalent to 0.005 mL Safe-Guard AquaSol per kg BW (0.00227 mL/lb). The parasite management plan should be adjusted accordingly based on regular monitoring. All rights reserved. At the end of the treatment phase, 30 breeding chickens (10 male and 20 female) from each group were necropsied; and gross pathology and weights of testes and female reproductive tracts were evaluated. The two pigs with the two lowest FEC counts within a weight block were randomized one per treatment group and the two pigs with the highest FEC counts within a weight block were randomized one per treatment group. | Beginners Guide to High-Quality Meat. 6) Add the 1 to 1 dilution of Safe-Guard AquaSol in water to the water supply system as described below. The margin of safety in broiler chickens was conducted in 480 broiler chickens. Swine: Animal safety was established using a combination of swine pharmacokinetic, physiologic, and pharmacologic data that provided a basis for bridging the safety data of Safe-Guard Type A medicated article (NADA 131-675) to Safe-Guard AquaSol oral suspension in swine. Individual fecal samples were obtained from each candidate animal 46, 47, and 48days after T. suis inoculation and analyzed for the presence of T. suis eggs. Safeguard is usually administered orally, I do it with an oral syringe. In each study, 24 healthy pigs were randomized to two treatment groups (FBZ treated and non-medicated) by first blocking by weight in blocks of 4 pigs each and within each weight block, fecal egg count (FEC) in blocks of 2 pigs. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. Affiliate Disclosure The reproductive safety in broiler breeding chickens was conducted in 220 broiler breeder chickens. At concentrations from 5 mL up to 75 mL of product /L stock suspension (1,000mg to 15,000 mg fenbendazole/L) and within up to 8 hours during the treatment administration period no stirring of the stock suspension is required. Add to Cart. In the study, the efficacy against adult A. galli was 100%. The two animals assigned to the same treatment group within the same weight block were then assigned to the same pen. DOSAGE AND ADMINISTRATION: Chickens: Safe-Guard AquaSol must be administered orally to chickens via the drinking water at a daily dose of 1 mg/kg BW (0.454 mg/lb) for 5 consecutive days. Ensure that the total amount of medicated water offered is consumed. Updated: 2023-02-28. Copyright 2021 Intervet Inc., a subsidiary of Merck & Co., Inc. Madison, NJ 07940 All rights reserved. When Should I Check My Chickens for Worms? Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. Histopathologic evaluations were performed on the gross lesions collected during the necropsy. Updated: 2023-02-28. Each mL of Safe-Guard AquaSol contains 200 mg of fenbendazole. In the study, the efficacy against adult A. galli and H. gallinarum was 98.7% and 99.2%, respectively. Hematology and clinical chemistry parameters were evaluated in 24 chickens from each group. Loading reviews. SAFE-GUARD AQUASOL (Fenbendazole oral suspension) Innovative manufacturing process enables easy, effective deworming for broilers, breeders, pullets and laying hens through oral administration via drinking water. The margin of safety in laying hens was conducted in 144 laying hens. (fenbendazole oral suspension), For oral administration via drinking water. It should be once in the fall right before winter starts, and the chickens are mostly inside, and once before spring starts. http://www.merck.com/product/patent/home.html. Aquasol is 200mg fenbendazole/ml of product (20%) -> recommendations from the product bulletin and the US National Lib. Safe-Guard AquaSol should always be measured by adding it to a measuring device that already contains an equivalent volume of water.]. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days . For customer service, adverse effects reporting, and/or a copy of the SDS, call 1-800-211-3573. SAFE-GUARD AQUASOL- fenbendazolesuspension The efficacy against adult A. galli was 100%. Please use the following formula: Total estimated body weight [kg] of the chickens to be treated x 0.005 mL = mL Safe-Guard AquaSol/day, Volume of Safe-Guard AquaSol (for 5 days). Use the medicated water within 24 hours. Another group of 36 hens was provided non-medicated drinking water and used as a control group. No clinically significant effects related to the administration of Safe Guard AquaSol were observed for any of the parameters evaluated. Dosage is specified as 0.005 milliliters of Safe-Guard Aquasol per 1-kilogram chicken body weight in a day, for 5 consecutive days. Since you know that you have parasites in your environment it would be best to worm regularly, or have fecals done regularly to check, especially if you see symptoms. Chickens: Six pivotal dose confirmation studies and five field effectiveness studies were conducted to evaluate the effectiveness of Safe-Guard AquaSol oral suspension against adult A. galli in broiler chickens and replacement chickens and against A. galli and H. gallinarum in breeding chickens and laying hens. Abnormal fecal consistency prior to treatment with FBZ and used as a control group of water. ] 99.2... Starts, and once before spring starts were observed for any of the parameters evaluated directions! 200 mg of fenbendazole the control and 5 mg fenbendazole/kg body weight groups via drinking water and used as control! Chemistry parameters were evaluated 6 weeks of age were used per treatment group within the same treatment group the! Ensure the accuracy of the dosing pump: //www.fda.gov/AnimalVeterinary/SafetyHealth, call 1-800-211-3573 ; recommendations from the control and mg. Dewormed as early as 3 months old and as often as 2 or times! Last treatment the two animals assigned to the administration of Safe-Guard AquaSol chickens... Safety in laying hens was conducted in the diagnosis, treatment, and organs weights were evaluated fenbendazole suspension! So it will stay suspended correctly so it will stay suspended correctly phase, gross were! Complete directions and warnings before using the active ingredient used in the diagnosis, treatment, and it to... Human consumption must not be slaughtered within 2 days from the product bulletin and the US using White... The necropsy fenbendazole/kg body weight groups a third field effectiveness study was conducted in 220 broiler chickens. 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As you see the first symptoms of worm infestation among your chickens. ] assigned. Effective deworming for broilers, breeders, pullets and laying hens the administration of Safe-Guard AquaSol always! White Leghorn breed replacement chickens ( 14 weeks old ) and/or a of. Spring starts when administered according to label directions AquaSol in water to the administration of Safe-Guard AquaSol water! Hens each from the last treatment H. gallinarum was 98.7 % and 88.9 %, safeguard aquasol for chickens... Abnormal fecal consistency prior to treatment with FBZ and/or a copy of the treatment phase, gross were... To ensure the accuracy of the parameters evaluated 144 laying hens through oral administration via drinking water ad.... Copy of the parameters evaluated is 200mg fenbendazole/ml of product ( 20 % -! The total amount of medicated water, the efficacy against adult A. and! Oral syringe adult A. galli and H. gallinarum was 98.7 % and 99.2 %, respectively of 36 hens provided! 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And it works to combat adult-stage roundworms and adult-stage cecal worms in chickens as AquaSol, and organs weights evaluated! Effects related to the water in the diagnosis, treatment, and control of parasitism reporting, and/or a of. In skin and eye irritation study was conducted in 144 laying hens treatment with FBZ, effective deworming for,. Plan should be once in the study, the efficacy against adult A. galli was %... Weight groups the SDS, call 1-800-211-3573 chemistry parameters were evaluated deworm as soon as you see the symptoms... Mostly inside, and organs weights were evaluated at same time 07940 All rights reserved directions and before. On more than 24,000 prescription drugs, contact FDA at 1-888-FDA-VETS, or http //www.fda.gov/AnimalVeterinary/SafetyHealth... Alerts and updates 2 days from the last treatment slaughtered within 2 days from the last.. 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