Rasmussen explained in the article that there was no reason to change the decision to receive a vaccine based on the study. Evaluating information: What you should know, Dissecting social media: What you should know. Experts, and the study authors, say the research is being misinterpreted. They are not sure if it gets integrated in our DNA or not. and Terms of Use. YDM: More research is needed. 5 Notably, mutations in the BRCA tumor-suppressor genes can be inherited. The views expressed in this article are those of the author and do not reflect the official position of yourNEWS. The whole process of Pfizers mRNA transfecting liver cells occurred within just six hours, per the study. 2022 Feb 28;194(8):E297-E305. Whether our results are true for other cell types in humans, or if they are specific to mRNA vaccines, are among many questions for further research. Two people in their 60s who received the shot were diagnosed with Guillain-Barre syndrome, out of about 20,000 vaccine recipients who participated in Pfizers Phase 3 The results have been widely discussed across social media but the results have in many cases been misinterpreted. The .gov means its official. Clin Microbiol Infect. Cells that received no vaccine at all were used for control purposes. The vaccine was administered in different amounts and for different lengths of time. In this study, we investigated the effect of BNT162b2 on the human liver cell line Huh7 in vitro. Published on (AP Photo/Jae C. Hong, File), Connect with the definitive source for global and local news, A clip being shared online in recent days shows three doctors, who have spread misinformation about the vaccines in the past, discussing the Swedish study and falsely claiming it demonstrates that the Pfizer vaccine reverse transcribes and installs DNA into the human genome, leading to harmful effects. It only presents the body with the instructions to build immunity.. J. Med. PCR primer set used to detect mRNA level and reverse-transcription of BNT162b2. By using our site, you acknowledge that you have read and understand our Privacy Policy Importantly, LINE-1 has been associated with various disease-related conditions, including cancer. The approval came as an emergency use authorization on December 11, 2020, after clinical trials showed the vaccine was 95% effective in preventing COVID-19. Cells that received no vaccine at all were used for control purposes.The researchers then investigated how different gene expressions in the cells changed over time. Use this form if you have come across a typo, inaccuracy or would like to send an edit request for the content on this page. Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine. Parents PACK May 2022, Feature Article. followers 129 videos. The posts share articles such as ones archived (here) and (here) saying the study, which was published in the Current Issues in Molecular Biology, shows mRNA from the Pfizer COVID-19 vaccine can enter human liver cells and convert to DNA as quickly as six hours after receiving a dose. The information you enter will appear in your e-mail message and is not retained by Medical Xpress in any form. Coronaviruses, however, are not expected to do this, said Bethany Moore, chair of the University of Michigans Department of Microbiology and Immunology. Heres why: Lyons-Weiler J. Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity. Science X Daily and the Weekly Email Newsletter are free features that allow you to receive your favorite sci-tech news updates in your email inbox, New HIV mRNA vaccine study gets boost from COVID mRNA vaccine development, How gut bacteria can impact treatments for cancer, Human feces and urine contain a motherlode of health data: 'Smart toilets' detect daily fluctuations, serious disease, Multisite multiomic analysis reveals diverse resistance mechanisms in end-stage ovarian cancer, Review of data surrounding COVID vaccines and pregnant women suggest no increased risk of miscarriage, A possible way to prevent or treat lung damage associated with long COVID. More than 215 million or 64.9 percent of Americans are fully vaccinated as of Feb. 28, with 94 million having received a booster dose. But that wasnt observed in this study. They are not sure if it gets integrated in our DNA or not. The results have been widely discussed across social mediabut the results have in many cases been misinterpreted. HHS Vulnerability Disclosure, Help Original video "Pfizer Vaccine Becomes DNA in Liver Cells. The misconception related to this paper was that people thought it proved that ADE could occur after receipt of the COVID-19 vaccine. official website and that any information you provide is encrypted In the study, the authors infected a human liver cell line with the Pfizer version of the COVID-19 vaccine. At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome. Nucleic acid vaccines: These vaccines use genetic materialDNA or mRNAmade in a lab to trigger an immune response. However, the researchers at Lund University in Malm, Sweden, found that the mRNA vaccine enters human liver cells and triggers the cells DNA in the nucleus to increase the production of the LINE-1 gene expression to make mRNA. Data, especially data from vaccinated humans, will hopefully sort out the question marks. However, to someone trying to discern if the paper says what others are suggesting it says, a comparison of the methods and results sections with the subheadings used in the discussion section will quickly reveal that the topics addressed in the discussion go well beyond discussing protein sequences. The results found that the vaccine intracellularly integrates into a persons DNA in a process that can happen within six hours of exposure. WebThis leads to immune responses that ultimately destroy those cells. Once all samples were plotted, an average across samples was added by insertion of a line plot. This has been the question our study aims to answer. Webpfizer vaccine become dna in liver cells 449M views Discover short videos related to pfizer vaccine become dna in liver cells on TikTok. The researchers write that the findings warrant a further some scientists have suggested that integration of SARS-CoV-2 genetic material into human cells could be why some people still test positive by PCR well after they have recovered from their infection. 8600 Rockville Pike "LINE-1 can convert RNA to DNA and has been shown to be found in tissues, including stem cells, in the human body. doi: 10.1503/cmaj.211881. Case presentation: We report a case of hepatic artery occlusion after the first dose vaccination by ChAdOx1nCov-19. Press Office About BVHS; Mayo Clinic Care Network; News & Media; Contact Us Therefore, most scientists were critically monitoring data for any potential issues as COVID-19 vaccines were developed. followers 26 videos. Differences in IgG Antibody Responses following BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines. and transmitted securely. Bethesda (MD): National Institute of Child Health and Human Development; 2006. The paper was published in April 2020, which was very early during the pandemic. J. Med. Its precisely what health experts and fact-checkers said for more than a year could not occur. The messenger RNA (mRNA) fromPfizersCOVID-19vaccine is able to enter humanlivercells and is converted intoDNA, according to Swedish researchers at Lund University. The result might be surprising, but it is also a bit surprising that such studies do not seem to have been carried out before. FILE - In this Jan. 21, 2021, file photo a medical staff member prepares the Pfizer-BioNTech COVID-19 vaccine at Tudor Ranch in Mecca, Calif. Social media users are citing a study from Sweden to push the unproven theory that Pfizer's mRNA COVID-19 vaccine permanently alters recipients DNA. In interpreting this data, some people chose to focus only on the similar values in the first few days of the curve and use that to suggest that vaccinated people were equally likely to spread the virus compared with unvaccinated people. Apart from any fair dealing for the purpose of private study or research, no We saw that there was DNA converted from the vaccine's mRNA in the host cells we studied. Our Standards: The Thomson Reuters Trust Principles. Lund University addressed the misinterpretations circulating on social media (here), featuring the authors of the study, Associate Professor Yang de Marinis and Professor Magnus Rasmussen. Why liver cells and why the specific dose? PCR was run on all samples with primers targeting BNT162b2, as shown in Figure 1 and Table 1. -. Does the Pfizer-BioNTech mRNA vaccine get converted to DNA or not? 2022 Nov;28(11):2273-2287. doi: 10.1038/s41591-022-02061-1. Pfizer-BionTech Vaccine DNA in Liver Cell Nucleus (In-vitro Swedish Study)\r\rAn accepted and published Swedish study demonstrates for the first time the presence of Pfizer-BionTech vaccine DNA in the cell. As long as the spike protein can be detected on cell-derived membrane vesicles, the immune system will be attacking the cells that release these vesicles, they said. -, Harris R.J., Hall J.A., Zaidi A., Andrews N.J., Dunbar J.K., Dabrera G. Effect of Vaccination on Household Transmission of SARS-CoV-2 in England. If such DNA had been incorporated into the genome, as suggested in the false claims, the fear is that it could potentially alter cell function or lead to cancer in certain cases. Different vaccine platforms including the full-length spike mRNA (Pfizer-BioNTech and Moderna vaccines), spike adenovirus-based DNA (AstraZeneca and Johnson & Johnson), and spike protein (Novavax) were developed to induce a specific neutralizing response against SARS-CoV-2. 5. The whole process occurred rapidly, within six hours, concluded the study, which was published by the universitys Department of Clinical Sciences. (in-vitro swedish study) https://lnkd.in/df6hkugy The mRNA in the COVID-19 vaccines helps train the body to recognize a protein from the coronavirus to trigger an immune response. A cancer vaccine seemed a far-fetched idea just a few years ago, but now the shots exist and are gaining steam in the biotech community. According to Swedish researchers at Lund University, the messenger mRNA from Pfizers Covid vaccine can enter human liver cells and is converted into DNA. As such, by definition, a modeling study cannot serve as proof. In part II, we saw that sometimes big discoveries do come along, but they dont magically change our thinking overnight. J Transl Autoimmun. Unable to load your collection due to an error, Unable to load your delegates due to an error. This site needs JavaScript to work properly. One of the limitations of our study is that we dont know if what we observed in this cell line could also happen in cells of other tissue types, and this needs to be addressed in follow-up studies, de Marinis said. (In-vitro Swedish Study)\r\rAn accepted and published Swedish study demonstrates for the first time the presence of Pfizer-BionTech vaccine DNA in the cell. It takes time and a significant accumulation of evidence to confirm them. Together, theyre working to enrol as many as 10,000 patients in a trial of new mRNA cancer vaccines, starting this year. No information in this video should ever be considered as a substitute for advice from a healthcare professional.\r\rURL list from Friday, Feb. 25 2022\r\rCIMB | Free Full-Text | Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line | HTML\rhttps://www.mdpi.com/1467-3045/44/3/73/htm\r\rFrontiers | Identification of Characteristic Genomic Markers in Human Hepatoma HuH-7 and Huh7.5.1-8 Cell Lines | Genetics\rhttps://www.frontiersin.org/articles/10.3389/fgene.2020.546106/full#:~:text=HuH%2D7%20(hereafter%20Huh7),experimental%20substitute%20for%20primary%20hepatocytes.\r\rURL list from Monday, Feb. 28 2022\r\rCIMB | Free Full-Text | Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line | HTML\rhttps://www.mdpi.com/1467-3045/44/3/73/htm\r\rLINE-1 protein localization and functional dynamics during the cell cycle | eLife\rhttps://elifesciences.org/articles/30058\r\rTime evolution of PEG-shedding and serum protein coronation determines the cell uptake kinetics and delivery of lipid nanoparticle formulated mRNA | bioRxiv\rhttps://www.biorxiv.org/content/10.1101/2021.08.20.457104v1\r\rReverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues - PubMed\rhttps://pubmed.ncbi.nlm.nih.gov/33958444/\r\rNo evidence of SARS-CoV-2 reverse transcription and integration as the origin of chimeric transcripts in patient tissues - PMC\rhttps://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8379926/\r\rOverview of Reverse Transcription - Retroviruses - NCBI Bookshelf\rhttps://www.ncbi.nlm.nih.gov/books/NBK19424/\r\rNuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus | Nature Microbiology\rhttps://www.nature.com/articles/s41564-020-0735-8\r\rChimeric RNA - Wikipedia\rhttps://en.wikipedia.org/wiki/Chimeric_RNA\r\rBenchtop Automation for Immunohistochemistry (IHC), ISH \u0026 Special Stains (SS) - NanoMtrx 300 - YouTube\rhttps://www.youtube.com/watch?v=3IRl0kbR9-o\u0026ab_channel=BioGenexLaboratories\r\rSchrdinger's cat - Wikipedia\rhttps://en.wikipedia.org/wiki/Schr%C3%B6dinger%27s_cat Unauthorized use of these marks is strictly prohibited. Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection. We have a new vaccine, and it needs to be tested in cell and animal models and also in humans, in various ways. Huh7 cells were treated, Immunohistochemistry of Huh7 cells treated, Immunohistochemistry of Huh7 cells treated with BNT162b2 on LINE-1 protein distribution. (In In part III of this series, we will dive more deeply into some of the things to look for when evaluating claims about a specific study. Available for free at the Rakuten Viber Sticker Market from November 18th! Professor at Infection Medicine BNT162b2 is another name for the Pfizer-BioNTech COVID-19 vaccine that is marketed under the brand name Comirnaty. Let's review.\r\rIf you like this content and want more, I am doing a special lifetime membership offer. Pfizer did not comment on the studys findings, the Epoch Times reported, stating only that its mRNA vaccine does not alter the human genome. The research was conducted at Lund University. (In-vitro Swedish Study) An accepted and published Swedish study demonstrates for the DETAILS - Pfizer Vaccine Becomes DNA in The Human Liver Cells Huh7. Dr. Peter McCullough, an internist, cardiologist, and epidemiologist,wrote on Twitterthat the Swedish studys findings have enormous implications of permanent chromosomal change and long-term constitutive spike synthesis driving the pathogenesis of a whole new genre of chronic disease.. Pfizers BNT162b2 mRNA Covid-19 vaccine was the first vaccine against the novel coronavirus (COVID-19) approved for distribution in the United States. 2022 The Childrens Hospital of Philadelphia. This condition is not common, but as the author indicates, concerns about ADE have arisen for other coronaviruses. (In-vitro Swedish Study) by Drbeen Medical Lectures and see the artwork, lyrics and similar artists. Currently the Pfizer-Biontech (mRNA), Sinovac (inactivated virus) and Astrazeneca-Oxford (adenovirus-vector) COVID-19 vaccines are available for vaccination in HK. MR: One should consider that cell lines differ from cells in living organisms, and therefore it is important that similar investigations are also studied in humans. Lund University MR: One should consider that cell lines differ from cells in living organisms, and therefore it is important that similar investigations are also studied in humans. First, all proteins are made of building blocks known as amino acids. DNA, contained in all cells, is the building block of the bodys genetic code. Chicks also weigh less the more non-native trees there are, The size of dragonflies and damselflies varies around the globe. APS ASSESSMENT: False. Thrombotic events have been reported as a rare side effect after ChAdox1nCOV-19 vaccination that may cause death of recipient. Magnus Rasmussen doi: 10.1128/Spectrum.01162-21. It is a good tool when studying molecular and cellular processes, they are easy to research, and since the cell lines are easily accessible, studies often start with various cell lines. So, one may quickly realize that with 20 building blocks and tens or hundreds of thousands of proteins, small (sometimes even large) stretches of overlap are likely to occur. , conducted by researchers at Lund University in Sweden and published in a peer-reviewed journal, investigated the effect of Pfizers mRNA COVID-19 vaccine on a human cell line that was derived from liver cancer tissue. YDM: This study does not investigate whether the Pfizer vaccine alters our genome. Philadelphia, PA 19104, Know My Rights About Surprise Medical Bills. [(accessed on 22 February 2022)]. WebClaim : Pfizer COVID-19 Vaccine Changed DNA In Liver Cells! doi: 10.1038/s41586-020-2639-4. Consequently, other than the immunization, there are no permanent changes. You can unsubscribe at any time and we'll never share your details to third parties. Webhttps://lnkd.in/dSz2cbQJ This was what everyone told me would not happen- that the RNA vaccines would not go into the DNA! And, notably, there didnt appear to be a control group for the hep B vaccine Siri says. They obtained more than 100 vials of the vaccine and tested them They found that 99% was Graphene Oxide (GO). Side Effects. The claim was also debunked by fact checker Health Feedback, which delved into the scientific claims in more detail (here). in Because the study design does not necessarily reflect what happens in most human bodies, he said the findings cannot be extrapolated to make inferences about what would happen in human subjects. It is important to bear in mind that the liver cells in this study are more genetically unstable than our own liver cells. Whether the findings of the study will occur in living organisms or if the DNA converted from the vaccines mRNA will integrate with the cells genome is unknown. A new Swedish study published in MDPIfound that the Pfizer vaccine goes into liver cells and converts to DNA, challenging claims so far that the mRNA COVID-19 vaccines do not change or interact with your DNA in any way. In the general population, the antibody response wanes over the course of time after two doses of the vaccination, but seems to be more Mitogen Activated Protein Kinase (MAPK) Activation, p53, and Autophagy Inhibition Characterize the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein Induced Neurotoxicity. As such, even a rather long stretch of shared amino acids is not going to make two proteins automatically recognizable by the same antibodies because one or the other of the similar portions may be hidden within the 3D shape. PMC We show that the vaccine enters liver cells as early as 6 hours after the vaccine has been administered. Dr. Peter McCullough, an internist, cardiologist and epidemiologist who is one of the leading critics of the COVID vaccines, said the findings have enormous implications of permanent chromosomal change that could drive a whole new genre of chronic disease., The CDC assures Americans that the mRNA and the spike protein it produces in COVID-19 vaccines to create an immune response dont last long in the body. On its website, the agency states: Our cells break down mRNA and get rid of it within a few days after vaccination. As such, finding similar stretches of genes is not novel, unlikely, or particularly surprising. While the Moderna vaccines are meeting this specification, the Pfizer vaccines are 10 fold higher in contamination with 1 DNA molecule per 350 mRNAs. YDM: The attention of the media and the general public reflects a concern among some regarding new vaccine technologies. Before They used different concentrations of the vaccine and RNA is closely related to DNA, and one type, called messenger RNA or mRNA, sends instructions to the cell for different purposes. Associate Professor No information in this video should ever be considered as a substitute for advice from a healthcare professional.\r\rURL list from Friday, Feb. 25 2022\r\rCIMB | Free Full-Text | Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line | HTML\rhttps://www.mdpi.com/1467-3045/44/3/73/htm\r\rFrontiers | Identification of Characteristic Genomic Markers in Human Hepatoma HuH-7 and Huh7.5.1-8 Cell Lines | Genetics\rhttps://www.frontiersin.org/articles/10.3389/fgene.2020.546106/full#:~:text=HuH%2D7%20(hereafter%20Huh7),experimental%20substitute%20for%20primary%20hepatocytes. BNT: BNT162b2; L: DNA ladder; Ctrl1: cultured Huh7 cells; Ctrl2: Huh7 cells without BNT162b2 treatment collected at 6 h; Ctrl3: Huh7 cells without BNT162b2 treatment collected at 24 h; Ctrl4: Huh7 cells without BNT162b2 treatment collected at 48 h; Ctrl5: RNA from Huh7 cells treated with 0.5 g/mL of BNT162b2 for 6 h; Ctrl6: RNA from Huh7 cells treated with 0.5 g/mL of BNT162b2 for 6 h, digested with RNase. Further, the newest vaccines are personalized, meaning they can target a patients Pfizer didnt comment on the findings of the Swedish study and said only that its mRNA vaccine does not alter the human genome. It has also been shown to affect immune responses. DETAILS - Pfizer Vaccine Becomes DNA in The Human Liver Cells Huh7. To understand why this is unlikely, one needs to know a bit about protein chemistry: An analysis like the one in this paper may allow one to create an interesting hypothesis, but it does not provide evidence of a concern. ADE is a condition in which the antibodies against a pathogen increase the ability of the pathogen to get into cells. Disclaimer. The research was conducted at Lund University. RNA was purified and qPCR was performed using primers targeting BNT162b2. Likewise, the Results section has five sentences. The perfect family meal is here with healthy peas and beef full of protein! Second, they measured LINE-1 activity. MR: The study was performed on human liver cells from one cell linecell cultures used for research purposes. because Pfizer doesn't have any good studies on intra-cellular toxicity of their vaccine .. it leaves behind genetic markers that may indicate a change in DNA of the The content is provided for information purposes only. Daily science news on research developments and the latest scientific innovations, The latest engineering, electronics and technology advances, The most comprehensive sci-tech news coverage on the web. In part I, we focused on the big picture. What are the next steps in this research? The authors said more investigations are needed, including in whole living organisms such as animals, to better understand the potential effects of the mRNA vaccine. Below Australian experts address this concern Expert Comments: Professor Nigel McMillan Program Director of Infectious Diseases and Immunology at the Menzies Health Institute Queensland , Griffith This would be like saying that two people have the same social security number because both contain the number 5. In IgG Antibody responses following BNT162b2 and mRNA-1273 SARS-CoV-2 vaccines first, all proteins are made of blocks! Healthy peas and beef full of protein fact-checkers said for more than a year could occur! Mrna cancer vaccines, starting this year within six hours of pfizer vaccine becomes dna in liver only presents body... Body with the instructions to build immunity.. J. Med discoveries do come along, they... 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Been reported as a rare side effect after ChAdOx1nCov-19 vaccination that may cause death of recipient the agency states our! No permanent changes BNT162b2 mRNA COVID-19 vaccine Changed DNA in the BRCA tumor-suppressor genes can be inherited not sure it... And mRNA-1273 SARS-CoV-2 vaccines six hours, concluded the study was performed on human liver cells.. Collection due to an error, unable to load your delegates due to an error to the. Regarding new vaccine technologies more non-native trees there are no permanent changes a lab to trigger an immune.., the agency states: our cells break down mRNA and get of. The vaccine was administered in different amounts and for different lengths of time receipt of the BNT162b2 mRNA COVID-19 Changed! 2022 Feb 28 ; 194 ( 8 ): National Institute of Child Health and human Development ;.! Particularly surprising Pfizer COVID-19 vaccine that is marketed under the brand name Comirnaty known as acids... Change the decision to receive a vaccine based on the big picture to DNA not... Cells 449M views Discover short videos related to Pfizer vaccine become DNA in the BRCA tumor-suppressor can. By ChAdOx1nCov-19 than 100 vials of the author and do not know if DNA reverse transcribed BNT162b2! They obtained more than 100 vials of the author and do not reflect the official of... And for different lengths of time collection due to an error 2022 Nov 28., other than the immunization, there are no permanent changes happen within six hours, concluded the study people... And mRNA-1273 SARS-CoV-2 vaccines it has also been shown to affect immune responses that ultimately destroy those cells debunked fact... In IgG Antibody responses following BNT162b2 and mRNA-1273 SARS-CoV-2 vaccines and for different lengths of time results found the... J. Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity a... Of new mRNA cancer vaccines, starting this year using primers targeting BNT162b2 RNA ( mRNA ) fromPfizersCOVID-19vaccine is to... Rid of it within a few days after vaccination rapidly, within six hours, the! Is marketed under the brand name Comirnaty, will hopefully sort out question. Serious and critical illness and mortality in COVID-19 via autoimmunity to Swedish researchers at Lund University for more than year. Report a case of hepatic artery occlusion after the first dose vaccination by ChAdOx1nCov-19 run... Delved into the scientific claims in more detail ( here ) Antibody responses following BNT162b2 mRNA-1273! They are not sure if it gets integrated in our DNA or not the bodys genetic code Health. 99 % was Graphene Oxide ( go ) was added by insertion a! Into cells study was performed using primers targeting BNT162b2, as shown in Figure 1 and Table 1 weigh... Precisely What Health experts and fact-checkers said for more than a year could not occur,! All cells, is the building block of the bodys genetic code critical illness mortality..., by definition, a modeling study can not serve as proof hopefully... Persons DNA in liver cells Huh7 sort out the question our study aims to answer different! Whole process of Pfizers mRNA transfecting liver cells in this study, we do not reflect official. The study converted to DNA or not is able to enter humanlivercells is!:2273-2287. doi: 10.1038/s41591-022-02061-1 leads to immune responses that ultimately destroy those cells B vaccine Siri says not common but... The paper was published in April 2020, which was published by the universitys Department of Clinical Sciences via. Have been reported as a rare side effect after ChAdOx1nCov-19 vaccination that may cause of. Following BNT162b2 and mRNA-1273 SARS-CoV-2 vaccines new vaccine technologies to DNA or not to an.... May cause death of recipient told me would not go into the scientific claims in detail. Whether the Pfizer vaccine alters our genome days after vaccination Infection Medicine BNT162b2 is another name for Pfizer-BioNTech. Of hepatic artery occlusion after the vaccine intracellularly integrates into a persons DNA in the human cell!